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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 14-3-3 protein zeta/delta

UniprotKB/SwissProt ID: 1433Z_MOUSE (P63101)

Gene Name: Ywhaz

Organism: Mus musculus (Mouse).

Function: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Melanosome. Note=Located to stage I to stage IV melanosomes (By similarity).

Network with metabolic pathway:
Kegg map ID Pathway Link
map04110Cell cycle
map04114Oocyte meiosis
map04151PI3K-Akt signaling pathway
map05161Hepatitis B
map05169Epstein-Barr virus infection
map05203Viral carcinogenesis
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000308

The S-nitrosylation sites of 1433Z_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
125QAERYDDMAA C MKSVTEQGAE HHHHHHHHHH H HHHHHHCCCC 2.27%MC1124926564-
225QAERYDDMAA C MKSVTEQGAE HHHHHHHHHH H HHHHHHCCCC 2.27%MC1120925432in vivo
325QAERYDDMAA C MKSVTEQGAE HHHHHHHHHH H HHHHHHCCCC 2.27%MC1121278135in vitro
425QAERYDDMAA C MKSVTEQGAE HHHHHHHHHH H HHHHHHCCCC 2.27%MC1122865876in vivo
594EKIETELRDI C NDVLSLLEKF HHHHHHHHHH H HHHHHHHHHH 4.10%MC0322588120-
694EKIETELRDI C NDVLSLLEKF HHHHHHHHHH H HHHHHHHHHH 4.10%MC0321278135in vitro
794EKIETELRDI C NDVLSLLEKF HHHHHHHHHH H HHHHHHHHHH 4.10%MC0322865876in vivo