logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: HLA class I histocompatibility antigen, Cw-3 alpha chain

UniprotKB/SwissProt ID: 1C03_HUMAN (P04222)

Gene Name: HLA-C

Synonyms: HLAC

Organism: Homo sapiens (Human).

Function: Involved in the presentation of foreign antigens to the immune system.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane; Single-pass type I membrane protein.

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Network with metabolic pathway:
Kegg map ID Pathway Link
map04612Antigen processing and presentation
map04940Type I diabetes mellitus
map05320Autoimmune thyroid disease
map05330Allograft rejection
map05332Graft-versus-host disease
map04650Natural killer cell mediated cytotoxicity
map05416Viral myocarditis
map04145Phagosome
map04514Cell adhesion molecules (CAMs)
map05166HTLV-I infection
map05168Herpes simplex infection
map05169Epstein-Barr virus infection
map05203Viral carcinogenesis
map04144Endocytosis
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001039
IPR003006
IPR003597
IPR007110
IPR010579
IPR011161
IPR011162
IPR013783

The S-nitrosylation sites of 1C03_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1125GSHIIQRMYG C DVGPDGRLLR CCEEEEEEEE E EECCCCEEEE 1.80%HC1025040305in vivo