Protein Name: Aspartate aminotransferase, mitochondrial
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UniprotKB/SwissProt ID: AATM_HUMAN (P00505)
Gene Name: GOT2
Organism: Homo sapiens (Human).
Function: Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion matrix. Cell membrane. Note=Exposure to alcohol promotes translocation to the cell membrane.
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | OMIM | 138150 | GLUTAMATE OXALOACETATE TRANSAMINASE, MITOCHONDRIAL; GOT2 ;;ASPARTATE AMINOTRANSFERASE, MITOC |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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