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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: ATP-binding cassette sub-family E member 1

UniprotKB/SwissProt ID: ABCE1_MOUSE (P61222)

Gene Name: Abce1

Synonyms: Rli

Organism: Mus musculus (Mouse).

Function: Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm (By similarity). Mitochondrion (By similarity). Note=Localized to clusters of virus formation at the plasma membrane (By similarity).

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001450
IPR003439
IPR003593
IPR007209
IPR013283

The S-nitrosylation sites of ABCE1_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1201KDETKTQAIV C QQLDLTHLKE HHHHHHHHHH H HHHCCCCCCC 1.42%MC0322865876in vivo