Protein Name: ATP-binding cassette sub-family E member 1
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UniprotKB/SwissProt ID: ABCE1_MOUSE (P61222)
Gene Name: Abce1
Synonyms: Rli
Organism: Mus musculus (Mouse).
Function: Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm (By similarity). Mitochondrion (By similarity). Note=Localized to clusters of virus formation at the plasma membrane (By similarity).
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Graphical Visualization of S-nitrosylation Sites:
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Overview of Protein S-nitrosylation Sites with Functional and Structural Information | |
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