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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Probable C->U-editing enzyme APOBEC-2

UniprotKB/SwissProt ID: ABEC2_MOUSE (Q9WV35)

Gene Name: Apobec2

Organism: Mus musculus (Mouse).

Function: Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR002125
IPR007904
IPR013158

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
2RPZ NMR - A46-224Link

The S-nitrosylation sites of ABEC2_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
171YSSGRNKTFL C YVVEVQSKGG CCCCCCEEEE E EEEEECCCCC 1.80%MC1021278135in vitro
271YSSGRNKTFL C YVVEVQSKGG CCCCCCEEEE E EEEEECCCCC 1.80%MC1022865876in vivo