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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Acyl-coenzyme A thioesterase 13

UniprotKB/SwissProt ID: ACO13_MOUSE (Q9CQR4)

Gene Name: Acot13

Synonyms: Them2

Organism: Mus musculus (Mouse).

Function: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Can also hydrolyze 3- hydroxyphenylacetyl-CoA (in vitro).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Mitochondrion.

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
2CY9 X-ray 2.72 A A/B1-140Link

The S-nitrosylation sites of ACO13_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
140LVSAAPEKLI C EMKVEEQHTN   6.39%MC1221278135in vitro
274VDSISTMALM C TERGAPGVSV   3.58%MC1221278135in vitro
374VDSISTMALM C TERGAPGVSV   3.58%MC1222865876in vivo