Protein Name: Acyl-coenzyme A thioesterase 1
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UniprotKB/SwissProt ID: ACOT1_MOUSE (O55137)
Gene Name: Acot1
Synonyms: Cte1
Organism: Mus musculus (Mouse).
Function: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. True acyl-CoA thioesterase being highly specific for saturated C12-C20 acyl-CoAs, with only a very low activity with decanoyl-CoA as substrate. Most active on myristoyl- and palmitoyl-CoA. Introduction of one or two double bonds decreases the activity to about half. No detectable activity with bile acid CoAs such as choloyl-CoA and chenodeoxycholoyl-CoA.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm.
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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