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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Actin, aortic smooth muscle

UniprotKB/SwissProt ID: ACTA_HUMAN (P62736)

Gene Name: ACTA2

Synonyms: ACTSA, ACTVS

Organism: Homo sapiens (Human).

Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton.

Network with metabolic pathway:
Kegg map ID Pathway Link
map04270Vascular smooth muscle contraction
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR004000
IPR004001

The S-nitrosylation sites of ACTA_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1219EIVRDIKEKL C YVALDFENEM HHHHHHHHHE E ECCCCHHHHH 3.68%HC0921278135in vitro
2259VITIGNERFR C PETLFQPSFI EEEECCHHHH H HHHHCCHHHC 3.08%HC0221278135in vitro
3287HETTYNSIMK C DIDIRKDLYA HHHHHHHHHC C CHHHHHHHHC 2.83%HC0221278135in vitro
4376EAGPSIVHRK C F--------- HHCHHHHHCC C5.02%HC0221278135in vitro