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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Actin, cytoplasmic 1

UniprotKB/SwissProt ID: ACTB_MOUSE (P60710)

Gene Name: Actb

Organism: Mus musculus (Mouse).

Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs (By similarity).

Network with metabolic pathway:
Kegg map ID Pathway Link
map05412Arrhythmogenic right ventricular cardiomyopathy (ARVC)
map04520Adherens junction
map04670Leukocyte transendothelial migration
map05100Bacterial invasion of epithelial cells
map05410Hypertrophic cardiomyopathy (HCM)
map05414Dilated cardiomyopathy
map05416Viral myocarditis
map04145Phagosome
map04510Focal adhesion
map04530Tight junction
map04810Regulation of actin cytoskeleton
map05132Salmonella infection
map05164Influenza A
map04971Gastric acid secretion
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR004000
IPR004001
The S-nitrosylation sites of ACTB_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
117ALVVDNGSGM C KAGFAGDDAP EEEEECCCCE E EEECCCCCCC 2.89%MC1322865876in vivo
2217EIVRDIKEKL C YVALDFEQEM HHHHHHHHHH E ECCCCHHHHH 3.68%MC0122178444-
3217EIVRDIKEKL C YVALDFEQEM HHHHHHHHHH E ECCCCHHHHH 3.68%MC0124895380-
4217EIVRDIKEKL C YVALDFEQEM HHHHHHHHHH E ECCCCHHHHH 3.68%MC0119101475-
5217EIVRDIKEKL C YVALDFEQEM HHHHHHHHHH E ECCCCHHHHH 3.68%MC0122865876in vivo
6257VITIGNERFR C PEALFQPSFL EEEECCHHHH H HHHHCCCHHC 3.08%MC1322178444-
7257VITIGNERFR C PEALFQPSFL EEEECCHHHH H HHHHCCCHHC 3.08%MC1318283105-
8257VITIGNERFR C PEALFQPSFL EEEECCHHHH H HHHHCCCHHC 3.08%MC1320837516in vivo
9257VITIGNERFR C PEALFQPSFL EEEECCHHHH H HHHHCCCHHC 3.08%MC1322865876in vivo
10272FQPSFLGMES C GIHETTFNSI CCCHHCCCCC C CHHHHHHHHH 3.65%MC1222178444-
11272FQPSFLGMES C GIHETTFNSI CCCHHCCCCC C CHHHHHHHHH 3.65%MC1224926564-
12272FQPSFLGMES C GIHETTFNSI CCCHHCCCCC C CHHHHHHHHH 3.65%MC1218283105-
13272FQPSFLGMES C GIHETTFNSI CCCHHCCCCC C CHHHHHHHHH 3.65%MC1220837516in vivo
14272FQPSFLGMES C GIHETTFNSI CCCHHCCCCC C CHHHHHHHHH 3.65%MC1222865876in vivo
15285HETTFNSIMK C DVDIRKDLYA HHHHHHHHHC C CHHHHHHHHC 3.22%MC0222178444-
16285HETTFNSIMK C DVDIRKDLYA HHHHHHHHHC C CHHHHHHHHC 3.22%MC0224895380-
17285HETTFNSIMK C DVDIRKDLYA HHHHHHHHHC C CHHHHHHHHC 3.22%MC0224926564-
18285HETTFNSIMK C DVDIRKDLYA HHHHHHHHHC C CHHHHHHHHC 3.22%MC0218283105-
19285HETTFNSIMK C DVDIRKDLYA HHHHHHHHHC C CHHHHHHHHC 3.22%MC0222865876in vivo
20374ESGPSIVHRK C F--------- HHHHHHHHHC C C 5.02%MC0922178444-
21374ESGPSIVHRK C F--------- HHHHHHHHHC C C 5.02%MC0918283105-