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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Actin, alpha cardiac muscle 1

UniprotKB/SwissProt ID: ACTC_HUMAN (P68032)

Gene Name: ACTC1

Synonyms: ACTC

Organism: Homo sapiens (Human).

Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton.

Protein disease:
Disease database Database Entry Disease information
HPRD00015Cardiomyopathy, dilated, 1R
HPRD00015Cardiomyopathy, familial hypertrophic
Network with metabolic pathway:
Kegg map ID Pathway Link
map04260Cardiac muscle contraction
map05410Hypertrophic cardiomyopathy (HCM)
map05414Dilated cardiomyopathy
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR004000
IPR004001

The S-nitrosylation sites of ACTC_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1219EIVRDIKEKL C YVALDFENEM HHHHHHHHHH E ECCCCHHHHH 3.68%HC1125040305in vivo