Protein Name: Alpha-actinin-1
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UniprotKB/SwissProt ID: ACTN1_HUMAN (P12814)
Gene Name: ACTN1
Organism: Homo sapiens (Human).
Function: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line. Cell membrane (By similarity). Cell junction (By similarity). Cell projection, ruffle (By similarity). Note=Colocalizes with MYOZ2 and PPP3CA at the Z-line of heart and skeletal muscle. Co
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PDB :
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | OMIM | 102575 | ACTININ, ALPHA-1; ACTN1 | | OMIM | 615193 | BLEEDING DISORDER, PLATELET-TYPE, 15; BDPLT15 |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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