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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Retinal dehydrogenase 1

UniprotKB/SwissProt ID: AL1A1_MOUSE (P24549)

Gene Name: Aldh1a1

Synonyms: Ahd-2, Ahd2, Aldh1

Organism: Mus musculus (Mouse).

Function: In addition to the activity on acetaldehyde and related substrates, is also involved in the oxidation of aldehydes derived from biogenic amines such as epinephrine and norepinephrine, as well as the aldehydes generated via lipid peroxidation. Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm.

Network with metabolic pathway:
Kegg map ID Pathway Link
map00830Retinol metabolism
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR015590

The S-nitrosylation sites of AL1A1_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1186FIWKIGPALS C GNTVVVKPAE HHHHHHHHHH H CCEEEECCCH 5.18%MC1120837516in vivo