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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Aldehyde dehydrogenase family 8 member A1

UniprotKB/SwissProt ID: AL8A1_MOUSE (Q8BH00)

Gene Name: Aldh8a1

Synonyms: Raldh4

Organism: Mus musculus (Mouse).

Function: Converts 9-cis-retinal to 9-cis-retinoic acid. Has lower activity towards 13-cis-retinal. Has much lower activity towards all-trans-retinal. Has a preference for NAD, but shows considerable activity with NADP (in vitro) (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm.

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

The S-nitrosylation sites of AL8A1_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1247ERITQLSAPH C KKLSLELGGK   3.96%MC0622178444-
2247ERITQLSAPH C KKLSLELGGK   3.96%MC0620837516
(Cys347)
in vivo
3354KAQTEGARIL C GEGVDQLSLP   4.31%MC1322178444-
4354KAQTEGARIL C GEGVDQLSLP   4.31%MC1320837516in vivo