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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Aldehyde dehydrogenase, mitochondrial

UniprotKB/SwissProt ID: ALDH2_MOUSE (P47738)

Gene Name: Aldh2

Synonyms: Ahd-1, Ahd1

Organism: Mus musculus (Mouse).

Function: Is capable of converting retinaldehyde to retinoic acid.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix.

Network with metabolic pathway:
Kegg map ID Pathway Link
map00010Glycolysis / Gluconeogenesis
map00040Pentose and glucuronate interconversions
map00053Ascorbate and aldarate metabolism
map00071Fatty acid metabolism
map00280"Valine, leucine and isoleucine degradation"
map00310Lysine degradation
map00330Arginine and proline metabolism
map00340Histidine metabolism
map00380Tryptophan metabolism
map00410beta-Alanine metabolism
map00561Glycerolipid metabolism
map00620Pyruvate metabolism
map00640Propanoate metabolism
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR015590
The S-nitrosylation sites of ALDH2_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
168TVNPSTGEVI C QVAEGNKEDV EECCCCCCEE E EEECCCHHHH 3.00%MC0522178444-
268TVNPSTGEVI C QVAEGNKEDV EECCCCCCEE E EEECCCHHHH 3.00%MC0519483679in vivo
368TVNPSTGEVI C QVAEGNKEDV EECCCCCCEE E EEECCCHHHH 3.00%MC0521278135in vitro
468TVNPSTGEVI C QVAEGNKEDV EECCCCCCEE E EEECCCHHHH 3.00%MC0522865876in vivo
5181SYTRHEPVGV C GQIIPWNFPL EEEEEEEEEE E EEECCCCCHH 2.46%MC0121278135in vitro
6181SYTRHEPVGV C GQIIPWNFPL EEEEEEEEEE E EEECCCCCHH 2.46%MC0122865876in vivo
7321FALFFNQGQC C CAGSRTFVQE HHHHCCCCCE E CCCCEEEECH 1.05%MC0422178444-
8321FALFFNQGQC C CAGSRTFVQE HHHHCCCCCE E CCCCEEEECH 1.05%MC0416242127-
9388SGQQEGAKLL C GGGAAADRGY HHHHCCCEEE E CCCCCCCCCC 7.44%MC1322178444-
10388SGQQEGAKLL C GGGAAADRGY HHHHCCCEEE E CCCCCCCCCC 7.44%MC1321278135in vitro
11388SGQQEGAKLL C GGGAAADRGY HHHHCCCEEE E CCCCCCCCCC 7.44%MC1320837516in vivo
12388SGQQEGAKLL C GGGAAADRGY HHHHCCCEEE E CCCCCCCCCC 7.44%MC1322865876in vivo
13474ALQAGTVWIN C YDVFGAQSPF HHCCCEEEEC C CCCCCCCCCC 1.95%MC1322865876in vivo