logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Aminopeptidase B

UniprotKB/SwissProt ID: AMPB_MOUSE (Q8VCT3)

Gene Name: Rnpep

Organism: Mus musculus (Mouse).

Function: Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin and Arg(- 1)-Lys(0)-somatostatin-14. Can hydrolyze leukotriene A4 (LTA-4) into leukotriene B4 (LTB-4) (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted.

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001930
IPR006025
IPR014782
IPR015211
IPR015571

The S-nitrosylation sites of AMPB_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1151TYRVGEGPGV C WLAPEQTAGK EEEECCCCEE E EECCEEECCC 2.82%MC1321278135in vitro
2181QAVLNRAFFP C FDTPAVKCTY CHHCCCEEEE C CCCCCCCCEE 3.99%MC0521278135in vitro
3369STILFGAAYT C LEAATGRALL HHHHCCHHHH H HHHHHHHHHH 1.79%MC0522865876in vivo