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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Acidic leucine-rich nuclear phosphoprotein 32 family member B

UniprotKB/SwissProt ID: AN32B_HUMAN (Q92688)

Gene Name: ANP32B

Synonyms: APRIL, PHAPI2

Organism: Homo sapiens (Human).

Function: Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Isoform 1: Nucleus. Note=Accumulates in the nuclei at the S phase (By similarity). Isoform 2: Cytoplasm. Note=Lacks a nuclear localization signal.

PDB :
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Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001611
IPR003603

The S-nitrosylation sites of AN32B_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
127AAVRELVLDN C KSNDGKIEGL CCCCEEEEEC C CCCCCCCCCH 5.23%HC012212679in vitro