UniprotKB/SwissProt ID: ANF_MOUSE (P05125)
Gene Name: Nppa
Synonyms: Pnd
Organism: Mus musculus (Mouse).
Function: Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted.
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PDB :
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