dbSNO 2.0

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Protein Name: Annexin A11

UniprotKB/SwissProt ID: ANX11_HUMAN (P50995)

Gene Name: ANXA11

Synonyms: ANX11

Organism: Homo sapiens (Human).

Function: Binds specifically to calcyclin in a calcium-dependent manner (By similarity). Required for midbody formation and completion of the terminal phase of cytokinesis.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Melanosome. Nucleus envelope. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle. Note=Found throughout the nucleoplasm at interphase and during mitosis concentrates around the mitotic apparatus (By similarity). Elevation of intracellular

Graphical Visualization of S-nitrosylation Sites:

Overview of Protein S-nitrosylation Sites with Functional and Structural Information

InterPro ID	Domain
IPR001464
IPR008157
IPR015475

The S-nitrosylation sites of ANX11_HUMAN

No.	Position	S-nitrosylated Peptide	Secondary Structure of S-nitrosylated Peptide	Solvent Accessibility of nitrosylated Site	Substrate Motifs	PubMed ID	Experiment
1	294	AIKGVGTDEA C LIEILASRSN	HHHCCCCHHH H HHHHHHCCCH	3.56%	HC07	22178444	-
2	294	AIKGVGTDEA C LIEILASRSN	HHHCCCCHHH H HHHHHHCCCH	3.56%	HC07	16648260	in vivo
3	294	AIKGVGTDEA C LIEILASRSN	HHHCCCCHHH H HHHHHHCCCH	3.56%	HC07	19483679	in vivo
4	384	TDESKFNAVL C SRSRAHLVAV	CCHHHHHHHH H CCCHHHHHHH	2.27%	HC05	24105792	-
5	384	TDESKFNAVL C SRSRAHLVAV	CCHHHHHHHH H CCCHHHHHHH	2.27%	HC05	19483679	in vivo
6	428	LEEGMLAVVK C LKNTPAFFAE	HHHHHHHHHH H HCCHHHHHHH	4.40%	HC02	24105792	-

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