UniprotKB/SwissProt ID: ARK72_MOUSE (Q8CG76)
Gene Name: Akr7a2
Synonyms: Afar, Akr7a5
Organism: Mus musculus (Mouse).
Function: Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Can reduce the dialdehyde protein- binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Golgi apparatus (By similarity). Cytoplasm (By similarity).
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