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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Actin-related protein 2

UniprotKB/SwissProt ID: ARP2_MOUSE (P61161)

Gene Name: Actr2

Synonyms: Arp2

Organism: Mus musculus (Mouse).

Function: Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton (By similarity). Cell projection (By similarity).

PDB :
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Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR004000

The S-nitrosylation sites of ARP2_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
111MDSQGRKVVV C DNGTGFVKCG CCCCCCCEEE E ECCCCEEEEE 1.96%MC1021278135in vitro
2221ETVRMIKEKL C YVGYNIEQEQ HHHHHHHHHH E ECCCCHHHHH 3.71%MC0121278135in vitro