Protein Name: Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
|
UniprotKB/SwissProt ID: AT2A1_HUMAN (O14983)
Gene Name: ATP2A1
Organism: Homo sapiens (Human).
Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.
| |
|
Protein disease:
|
| Disease database |
Database Entry |
Disease information | | KEGG | H01129 | Brody myopathy | | OMIM | 108730 | ATPase, Ca(2)-TRANSPORTING, FAST-TWITCH 1; ATP2A1 ;;SARCOPLASMIC RETICULUM Ca(2)-ATPase 1; | | OMIM | 601003 | BRODY MYOPATHY | | HPRD | 00157 | Brody myopathy |
|
Network with metabolic pathway:
|
|
Graphical Visualization of S-nitrosylation Sites:
|
| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
|
