Protein Name: Sarcoplasmic/endoplasmic reticulum calcium ATPase 3
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UniprotKB/SwissProt ID: AT2A3_HUMAN (Q93084)
Gene Name: ATP2A3
Organism: Homo sapiens (Human).
Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | OMIM | 601929 | ATPase, Ca(2)-TRANSPORTING, UBIQUITOUS; ATP2A3 ;;SARCOPLASMIC RETICULUM Ca(2)-ATPase 3; SE |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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