dbSNO 2.0

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Protein Name: BAG family molecular chaperone regulator 3

UniprotKB/SwissProt ID: BAG3_MOUSE (Q9JLV1)

Gene Name: Bag3

Synonyms: Bis

Organism: Mus musculus (Mouse).

Function: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

PDB :
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Graphical Visualization of S-nitrosylation Sites:

Overview of Protein S-nitrosylation Sites with Functional and Structural Information

InterPro ID	Domain
IPR001202
IPR003103

3D Structure Databases:


3D structure databases
Entry	Method	Resolution (A)	Chain	Positions	View
1UK5	NMR	-	A	406-503	Link

The S-nitrosylation sites of BAG3_MOUSE

No.	Position	S-nitrosylated Peptide	Secondary Structure of S-nitrosylated Peptide	Solvent Accessibility of nitrosylated Site	Substrate Motifs	PubMed ID	Experiment
1	154	MTEAAQTDKQ C GQMPATATTA	CCCCCCCCCC C CCCCCCCCCC	5.14%	MC09	21278135	in vitro
2	185	ERSQSPAASD C SSSSSSASLP	CCCCCCCCCC C CCCCCCCCCC	3.83%	MC08	21278135	in vitro
3	185	ERSQSPAASD C SSSSSSASLP	CCCCCCCCCC C CCCCCCCCCC	3.83%	MC08	22865876	in vivo
4	378	EVKVSSAPIP C PSPSPAPSAV	CCCCCCCCCC C CCCCCCCCCC	5.58%	MC13	21278135	in vitro

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