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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Catalase

UniprotKB/SwissProt ID: CATA_HUMAN (P04040)

Gene Name: CAT

Organism: Homo sapiens (Human).

Function: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Peroxisome.

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Protein disease:
Disease database Database Entry Disease information
HPRD00282Acatalasemia, Japanese type
Network with metabolic pathway:
Kegg map ID Pathway Link
map00380Tryptophan metabolism
map00630Glyoxylate and dicarboxylate metabolism
map05014Amyotrophic lateral sclerosis (ALS)
map04146Peroxisome
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR002226
IPR011614

The S-nitrosylation sites of CATA_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1232LVNANGEAVY C KFHYKTDQGI EECCCCCEEE E EEEEEECCCC 2.81%HC0625040305in vivo
2460VLNEEQRKRL C ENIAGHLKDA CCCHHHHHHH H HHHHHHHHCC 4.34%HC0924105792-