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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: F-actin-capping protein subunit alpha-2

UniprotKB/SwissProt ID: CAZA2_MOUSE (P47754)

Gene Name: Capza2

Synonyms: Cappa2

Organism: Mus musculus (Mouse).

Function: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR002189

The S-nitrosylation sites of CAZA2_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1141YVKEHYPNGV C TVYGKKVDGQ HHHHHCCCCE E EEEECCCCCC 1.95%MC0220925432in vivo
2157KVDGQQTIIA C IESHQFQAKN CCCCCEEEEE E EEECCCCCCC 2.21%MC0320925432in vivo