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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Carbonyl reductase [NADPH] 3

UniprotKB/SwissProt ID: CBR3_HUMAN (O75828)

Gene Name: CBR3

Organism: Homo sapiens (Human).

Function: Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm.

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Network with metabolic pathway:
Kegg map ID Pathway Link
map00590Arachidonic acid metabolism
map00980Metabolism of xenobiotics by cytochrome P450
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR002198
IPR002347

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
2HRB X-ray 1.90 A A6-276Link

The S-nitrosylation sites of CBR3_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1226RKADRILVNA C CPGPVKTDMD HCCCCEEEEE E CCCCCCCCCC 2.13%HC1219483679in vivo
2227KADRILVNAC C PGPVKTDMDG CCCCEEEEEE C CCCCCCCCCC 3.97%HC0119483679in vivo