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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 60 kDa heat shock protein, mitochondrial

UniprotKB/SwissProt ID: CH60_RAT (P63039)

Gene Name: Hspd1

Synonyms: Hsp60

Organism: Rattus norvegicus (Rat).

Function: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix (By similarity).

Network with metabolic pathway:
Kegg map ID Pathway Link
map04940Type I diabetes mellitus
map05134Legionellosis
map05152Tuberculosis
map03018RNA degradation
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001844
IPR002423
IPR008950
IPR012723

The S-nitrosylation sites of CH60_RAT

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1442VEEGIVLGGG C ALLRCIPALD HHCCCCCCCH H HHHHHHHHHH 2.46%RC0416418269in vitro