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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Choline/ethanolamine kinase

UniprotKB/SwissProt ID: CHKB_MOUSE (O55229)

Gene Name: Chkb

Synonyms: Chetk, Chkl

Organism: Mus musculus (Mouse).

Function: Has a key role in phospholipid biosynthesis. Catalyzes the first step in phosphatidylethanolamine biosynthesis. Phosphorylates ethanolamine, and can also act on choline (in vitro). Has higher activity with ethanolamine. May not significantly contribute to in vivo phosphatidylcholine biosynthesis (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Network with metabolic pathway:
Kegg map ID Pathway Link
map00564Glycerophospholipid metabolism
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR002573
IPR002575
IPR011009

The S-nitrosylation sites of CHKB_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
172RRARPEELSV C PVSGGLSNLL HCCCHHHEEE E EEECCCCCCE 2.18%MC0122178444-
272RRARPEELSV C PVSGGLSNLL HCCCHHHEEE E EEECCCCCCE 2.18%MC0119101475-