UniprotKB/SwissProt ID: CHRD1_HUMAN (Q9UHD1)
Gene Name: CHORDC1
Synonyms: CHP1
Organism: Homo sapiens (Human).
Function: Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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PDB :
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