Protein Name: Cysteine and histidine-rich domain-containing protein 1
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UniprotKB/SwissProt ID: CHRD1_MOUSE (Q9D1P4)
Gene Name: Chordc1
Synonyms: Chp1, Morgana
Organism: Mus musculus (Mouse).
Function: Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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Graphical Visualization of S-nitrosylation Sites:
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Overview of Protein S-nitrosylation Sites with Functional and Structural Information | |
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