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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Cytoskeleton-associated protein 4

UniprotKB/SwissProt ID: CKAP4_HUMAN (Q07065)

Gene Name: CKAP4

Organism: Homo sapiens (Human).

Function: High-affinity epithelial cell surface receptor for APF. Mediates the anchoring of the endoplasmic reticulum to microtubules.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Note=Translocates to the perinuclear region upon APF- stimulation.

Network with metabolic pathway:
Kegg map ID Pathway Link
map04141Protein processing in endoplasmic reticulum
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

The S-nitrosylation sites of CKAP4_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1100AAAAASSSAS C SRRLGRALNF HHHHCCCHHH H HHHHHHHHHH 3.52%HC0522178444-
2100AAAAASSSAS C SRRLGRALNF HHHHCCCHHH H HHHHHHHHHH 3.52%HC052212679in vitro
3100AAAAASSSAS C SRRLGRALNF HHHHCCCHHH H HHHHHHHHHH 3.52%HC0520140087in vivo