Protein Name: Clathrin heavy chain 1
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UniprotKB/SwissProt ID: CLH1_HUMAN (Q00610)
Gene Name: CLTC
Synonyms: CLH17, CLTCL2, KIAA0034
Organism: Homo sapiens (Human).
Function: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Melanosome. Note=Cytoplasmic face of coated pits and vesicles. Identified by mass spectrometry in melanosome
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Protein disease:
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Disease database |
Database Entry |
Disease information | OMIM | 118955 | CLATHRIN, HEAVY POLYPEPTIDE; CLTC ;;CLATHRIN HEAVY CHAIN; CHC CLTC/TFE3 FUSION GENE, INCLUDE |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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Overview of Protein S-nitrosylation Sites with Functional and Structural Information | |
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