Protein Name: Catechol O-methyltransferase
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UniprotKB/SwissProt ID: COMT_MOUSE (O88587)
Gene Name: Comt
Synonyms: Comt1
Organism: Mus musculus (Mouse).
Function: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Isoform Soluble: Cytoplasm. Isoform Membrane-bound: Cell membrane; Single-pass type II membrane protein; Extracellular side.
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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