Protein Name: Cytochrome P450 2F2
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UniprotKB/SwissProt ID: CP2F2_MOUSE (P33267)
Gene Name: Cyp2f2
Synonyms: Cyp2f-2
Organism: Mus musculus (Mouse).
Function: Involved in the regio- and stereoselective transformation of naphthalene to trans-1R-hydroxy-2R-glutathionyl- 1,2-dihydronaphthalene in the presence of glutathione and glutathione S-transferases. It specifically catalyzes the production of a very reactive and potentially toxic intermediate, the 2R,2S arene oxide, that is associated with necrosis of the unciliated bronchiolar epithelial cells or Clara cells in lung.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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Overview of Protein S-nitrosylation Sites with Functional and Structural Information | |
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