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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: C-terminal-binding protein 1

UniprotKB/SwissProt ID: CTBP1_HUMAN (Q13363)

Gene Name: CTBP1

Synonyms: CTBP

Organism: Homo sapiens (Human).

Function: Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus.

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Network with metabolic pathway:
Kegg map ID Pathway Link
map04330Notch signaling pathway
map05220Chronic myeloid leukemia
map04310Wnt signaling pathway
map05200Pathways in cancer
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR006139
IPR006140

The S-nitrosylation sites of CTBP1_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
154ILKDVATVAF C DAQSTQEIHE HHCCCEEEEE E CCCCCHHHHH 2.82%HC0724105792-
2350TGRIPDSLKN C VNKDHLTAAT CCCCCCCHHH C CCCCCCCCCC 3.22%HC0324105792-