Protein Name: Gap junction alpha-1 protein
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UniprotKB/SwissProt ID: CXA1_MOUSE (P23242)
Gene Name: Gja1
Synonyms: Cxn-43
Organism: Mus musculus (Mouse).
Function: Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract. Connexin 43 is possibly the ATP-induced pore of mouse macrophages.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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