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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

UniprotKB/SwissProt ID: DDAH1_BOVIN (P56965)

Gene Name: DDAH1

Organism: Bos taurus (Bovine).

Function: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR003198

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
2C6Z X-ray 1.20 A A2-285Link
2CI1 X-ray 1.08 A A8-282Link
2CI3 X-ray 1.70 A A2-285Link
2CI4 X-ray 1.70 A A2-285Link
2CI5 X-ray 1.79 A A/B2-285Link
2CI6 X-ray 2.00 A A2-285Link
2CI7 X-ray 1.60 A A2-285Link

The S-nitrosylation sites of DDAH1_BOVIN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1222LTVPDDTAAN C IYLNIPSKGH CCCCCCHHHH H HHHCCCCCCC 1.53%N/A12441345-
2274ELEKVDGLLT C SSVLINKKVD HHHHCCCCCE E EEEEECCCCC 2.62%N/A12441345-