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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Neutrophil defensin 1

UniprotKB/SwissProt ID: DEF1_HUMAN (P59665)

Gene Name: DEFA1

Synonyms: DEF1, DEFA2, MRS

Organism: Homo sapiens (Human).

Function: Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted.

PDB :
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Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR002366
IPR006080
IPR006081

The S-nitrosylation sites of DEF1_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
183CIAGERRYGT C IYQGRLWAFC CCCCCCEEEE E EECCEEEEEC 2.07%HC1225040305in vivo