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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Desmin

UniprotKB/SwissProt ID: DESM_MOUSE (P31001)

Gene Name: Des

Organism: Mus musculus (Mouse).

Function: Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm.

Network with metabolic pathway:
Kegg map ID Pathway Link
map05412Arrhythmogenic right ventricular cardiomyopathy (ARVC)
map05410Hypertrophic cardiomyopathy (HCM)
map05414Dilated cardiomyopathy
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001664
IPR006821

The S-nitrosylation sites of DESM_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1332EYRHQIQSYT C EIDALKGTND HHHHHHHHHH H HHHHHHHHHH 3.07%MC1121278135in vitro
2332EYRHQIQSYT C EIDALKGTND HHHHHHHHHH H HHHHHHHHHH 3.07%MC1122865876in vivo