Protein Name: Desmoplakin
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UniprotKB/SwissProt ID: DESP_MOUSE (E9Q557)
Gene Name: Dsp
Organism: Mus musculus (Mouse).
Function: Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin- plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell junction, desmosome (By similarity). Cytoplasm, cytoskeleton (By similarity). Note=Innermost portion of the desmosomal plaque. Colocalizes with epidermal KRT5-KRT14 and simple KRT8-KRT18 keratins and VIM intermediate filaments network (By similarity
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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