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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Destrin

UniprotKB/SwissProt ID: DEST_HUMAN (P60981)

Gene Name: DSTN

Synonyms: ACTDP, DSN

Organism: Homo sapiens (Human).

Function: Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers (G-actin). Acts in a pH- independent manner.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR002108
The S-nitrosylation sites of DEST_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1135KKKFQGIKHE C QANGPEDLNR HHHHCCEEEE E EECCHHHCCH 4.65%HC032212679in vitro
2135KKKFQGIKHE C QANGPEDLNR HHHHCCEEEE E EECCHHHCCH 4.65%HC0322126794in vivo
3147ANGPEDLNRA C IAEKLGGSLI ECCHHHCCHH H HHHHCCCCEE 2.46%HC0319483679in vivo