Protein Name: Glutamate dehydrogenase 1, mitochondrial
|
UniprotKB/SwissProt ID: DHE3_HUMAN (P00367)
Gene Name: GLUD1
Synonyms: GLUD
Organism: Homo sapiens (Human).
Function: Mitochondrial glutamate dehydrogenase that converts L- glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion matrix.
|
PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. ) |
|
Protein disease:
|
| Disease database |
Database Entry |
Disease information | | HPRD | 11748 | Hyperinsulinemic hypoglycemia, familial, 6 |
|
Network with metabolic pathway:
|
|
Graphical Visualization of S-nitrosylation Sites:
|
| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
|
