UniprotKB/SwissProt ID: DPH3_MOUSE (Q8K0W9)
Gene Name: Dph3
Synonyms: Desr1, Zcsl2
Organism: Mus musculus (Mouse).
Function: Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2. Down-regulation increases extracellular release of proteoglycans, indicating a possible role in the secretion process. Stimulates binding of GNEFR to SEC5 (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm (By similarity). Nucleus (By similarity).
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