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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: DNA polymerase alpha subunit B

UniprotKB/SwissProt ID: DPOA2_HUMAN (Q14181)

Gene Name: POLA2

Organism: Homo sapiens (Human).

Function: May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus.

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Network with metabolic pathway:
Kegg map ID Pathway Link
map00230Purine metabolism
map00240Pyrimidine metabolism
map03030DNA replication
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR007185
IPR013627

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
2KEB NMR - A1-78Link
4E2I X-ray 5.00 A 1/2/3/4/5/6/7/8/9/U/W1-78Link

The S-nitrosylation sites of DPOA2_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1198AGNISLKVLG C PEALTGSYKS CCCCEEEEEC C CCCCCCCHHH 2.11%HC0819483679in vivo