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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Cytoplasmic dynein 1 heavy chain 1

UniprotKB/SwissProt ID: DYHC1_HUMAN (Q14204)

Gene Name: DYNC1H1

Synonyms: DHC1, DNCH1, DNCL, DNECL, DYHC, KIAA0325

Organism: Homo sapiens (Human).

Function: Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton.

PDB :
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Network with metabolic pathway:
Kegg map ID Pathway Link
map04962Vasopressin-regulated water reabsorption
map04145Phagosome
map05132Salmonella infection
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

The S-nitrosylation sites of DYHC1_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
11999NYDKTSAPIT C ELLNKQVKVS   3.43%HC012212679in vitro