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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Cytoplasmic dynein 1 heavy chain 1

UniprotKB/SwissProt ID: DYHC1_MOUSE (Q9JHU4)

Gene Name: Dync1h1

Synonyms: Dhc1, Dnch1, Dnchc1, Dyhc

Organism: Mus musculus (Mouse).

Function: Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton.

PDB :
( If your security settings prevent Jmol from running, please register http://140.138.144.145/ as a safe location in your Java settings. )

Network with metabolic pathway:
Kegg map ID Pathway Link
map04962Vasopressin-regulated water reabsorption
map04145Phagosome
map05132Salmonella infection
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
3ERR X-ray 2.27 A A/B3260-3427Link
3J1T EM 9.70 A A3264-3427Link
3J1U EM 9.70 A A3264-3427Link

The S-nitrosylation sites of DYHC1_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1631FKVQYPQSQA C KMSHVRDLPP   2.70%MC0219101475-
24568VTGLKLQGAT C SNNKLSLSNA   3.98%MC0720925432in vivo