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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Trifunctional enzyme subunit alpha, mitochondrial

UniprotKB/SwissProt ID: ECHA_HUMAN (P40939)

Gene Name: HADHA

Synonyms: HADH

Organism: Homo sapiens (Human).

Function: Bifunctional subunit.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion.

Protein disease:
Disease database Database Entry Disease information
HPRD02934LChad deficiency
HPRD02934Neuropathy-myopathy, progressive, due to trifunctional protein deficiency
HPRD02934Trifunctional protein deficiency
Network with metabolic pathway:
Kegg map ID Pathway Link
map00062Fatty acid elongation
map00071Fatty acid metabolism
map00280"Valine, leucine and isoleucine degradation"
map00310Lysine degradation
map00380Tryptophan metabolism
map00410beta-Alanine metabolism
map00640Propanoate metabolism
map00650Butanoate metabolism
map01040Biosynthesis of unsaturated fatty acids
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001753
IPR006108
IPR006176
IPR006180
IPR008927
IPR012803
IPR013328

The S-nitrosylation sites of ECHA_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1322IEQGSDAGYL C ESQKFGELVM HHCCHHHHHH H HHHHHHHHHC 3.39%HC122212679in vitro