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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Enhancer of mRNA-decapping protein 4

UniprotKB/SwissProt ID: EDC4_HUMAN (Q6P2E9)

Gene Name: EDC4

Synonyms: HEDLS

Organism: Homo sapiens (Human).

Function: In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, P-body. Nucleus.

Network with metabolic pathway:
Kegg map ID Pathway Link
map03018RNA degradation
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001680
IPR011046
IPR015943