UniprotKB/SwissProt ID: EF1A1_HUMAN (P68104)
Gene Name: EEF1A1
Synonyms: EEF1A, EF1A, LENG7
Organism: Homo sapiens (Human).
Function: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus. Note=Colocalizes with DLC1 at actin-rich regions in the cell periphery.
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