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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: EF-hand domain-containing protein D2

UniprotKB/SwissProt ID: EFHD2_HUMAN (Q96C19)

Gene Name: EFHD2

Synonyms: SWS1

Organism: Homo sapiens (Human).

Function: May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane raft (By similarity). Note=In a mouse immature B-cell line WEHI-231 (By similarity).

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR002048
IPR011992

The S-nitrosylation sites of EFHD2_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1172AGELQEDSGL C VLARLSEIDV CCCCHHHHHH H HHHHHCHHCC 2.41%HC1222178444-